Chasing the Mysteries of Microbiome Communication in Our Bodies
When we hear about gut bacteria, we may think about probiotics and supplements marketed to help with digestion, about how taking antibiotics might affect our intestinal tract, or perhaps about trendy diets that aim to improve gut health. But two researchers at Penn...
Advances in the Microbiome, Immunity and Cancer interplay
Gut microbiome plays an important role in colorectal cancer (CRC) initiation, progression and response to different systemic therapies. On its turn, gut microbiome is influenced by host factors (race, sex, genetic predisposition, oxidative stress, metabolic and...
Functional biotransformation of phytoestrogens by gut microbiota with impact on cancer treatment
The human gut is a host for trillions of microorganisms, divided into more than 3,000 heterogeneous species that is called the gut microbiota. The gut microbiota composition can be altered by many different endogenous and exogenous factors, especially diet and...
Gut microbiome immaturity and childhood acute lymphoblastic leukaemia
Acute lymphoblastic leukaemia (ALL) accounts for one-third of paediatric cancer cases in developed societies1. Although treatment of paediatric ALL is highly successful with cure rates of around 90%2, the longer-term complications of therapy and impact on quality of...
